ABSTRACT
Background: The Aim of the study was to analyze the functional outcome of limb length discrepancy after total hip replacement. . Methods: It is a Prospective study on 21 patients who underwent total hip replacement with different hip pathology between November 2015 and October 2017. Results: 13 males and 8 females patients with a mean age of 35.31±7.42 (21-50) were followed up for a time of 12months. Limb length discrepancy and hip function of 21 patients who underwent primary total hip arthroplasty were assessed before surgery and 1month, 3 month and 12 month after surgery. Limb length discrepancy was evaluated before and after surgery by clinical and radiological method, Functional outcome assessed by using the Oxford hip score (OHS) and Harris hip score(HHS). Preoperatively all patients had shorter limb length as compared to contra lateral side. Postoperatively in 42.9% (9/21) the limb operated on was longer, in 19 %( 4/21) of cases limb operated on was shorter and in 31 %( 8/21) postoperative limb length were equal. Postoperatively limb length discrepancy was present in 61.9 %( 13/21) & was perceived by 53.8 %( 7/13 of cases) when either shortening or lengthening exceeded 10mm. Oxford hip score (OHS) and Harris hip score (HHS) were significantly increased at subsequent follow up (at 1, 3 and 12 months). Functional scores (OHS and HHS) were excellent in patients with equal limb length as compared to those having shorter or longer limb length. Conclusion: Patient with limb length discrepancy had negative influence in relation to limping and pain. Patients should be counseled preoperatively about possible limb length differences and associated symptoms.
ABSTRACT
Aims: Viola odorata is a medicinally important plant. It contains bioactive principle viz violin and probably methyl salicylic ester. The present study was designed to analyze the effect of different doses of this medicinal plant extract on meiotic and mitotic chromosomes of Vicia faba. Study Design: In this study, different concentrations (5, 10, 20, 30, 40, & 50 %) of Viola odorata extract were applied for 4, 8, 12 and 24h on Vicia faba plant. Effect of these concentrations was studied on the meiotic and mitotic chromosomes. Gesticulate negative activity of herbal medicine was observed under the effect of different concentrations of the extract. Place and Duration of Study: The extract of Viola odorata was prepared in the laboratory. Study was performed from January, 2011 to December, 2012. Methodology: Flower bud treatment method was applied for meiotic analysis and seed soaked & root tip treatment methods were used for mitotic analysis. Mitotic and meiotic chromosome indicated various abnormalities against different doses. Cytotoxicity was inferred when the Mitotic index (dividing cells/1000 scored) of treated cells was significantly different (P<0.05) from control. Results: The percent of their abnormalities increase with increasing dose (5-50%) and time (4-24 hours) dependent. Low dose treatment of buds caused increase in mitotic index. Treated roots were found negatively affected with no exception and found more harmful and effective compared to seed soaked treatment. Stickiness was more frequent than other abnormalities. Conclusion: Vicia faba chromosome analysis is indicative of clastogenic action of Viola odorata. Thus, results of the present study suggest the doses of Viola odorata extract to verify the toxic properties before using for treatment.